Though some people are blessed with good genes and perfect health, for most of us, wellness is something we have to work at. Along with eating a balanced diet, exercising, getting enough sleep, and other positive and productive habits, supplements can be a valuable part of your health regimen. 

CBD is one of the most widely-used health supplements, a naturally-occurring chemical compound that interacts with the body’s endocannabinoid system (ECS). The ECS, which is responsible for maintaining homeostasis in several bodily functions and processes, contains cannabinoids of its own, cannabinoid receptors, and enzymes. CBD works by helping the ECS work more effectively. 

From vitamins and minerals to herbs and amino acids, many supplements work similarly by helping certain parts of the brain and body function better. Like diet and exercise or tea and honey, certain supplements make a perfect pair. Such is the case with CBD and these seven other natural medicinals.

7 Supplements That Complement CBD 


L-theanine is an amino acid found in green and black tea widely used to reduce stress and anxiety. While it doesn’t produce any drowsiness, pairing it with caffeine is beneficial because it can help improve focus and concentration. L-theanine can also promote a healthy immune system and regular sleep cycles. Research also indicates it may provide sinusitis relief and help regulate blood pressure. 

Vitamin D

Known as the “sunshine vitamin,” D is another multifaceted supplement. Except unlike l-theanine, the body produces vitamin D naturally when the skin is exposed to sunlight. If you don’t live in an area with year-round sunshine, you may want to take a supplement, as this vitamin plays a vital role in health and wellness. It’s essential for maintaining a balanced mood, and deficiency can contribute to depression. It is also crucial in supporting immune system function and may reduce your risk of the flu and autoimmune diseases such as multiple sclerosis. Vitamin D helps keep bones, teeth, and muscles healthy as well. 


Commonly referred to as 5-HTP or oxitriptan, 5-Hydroxytryptophan is a naturally-occurring amino acid that helps the body produce serotonin, a neurotransmitter known as the “happiness chemical.” Serotonin plays a role in mood, sleep, appetite, and digestion. Low levels are often associated with depression, insomnia, excess weight gain, and other ailments.

Evening Primrose Oil

Evening primrose is a plant native to North and South America. The oil extracted from these plants contains polyphenols and linoleic acid, and Gamma-Linolenic Acid (GLA), all of which can have health benefits. Specifically, many people use it to treat issues like premenstrual syndrome (PMS) and menopause symptoms. Applied topically, it may promote clear, healthy skin.


Chasteberry is another plant-based medicinal supplement. Also known as Vitex agnus-castus, it’s derived from the chaste berry plant or chaste tree. It’s usually used to ease PMS symptoms and help with perimenopause and menopause symptoms, infertility, nursing, and acne.


Several studies have suggested CBD has analgesic and anti-inflammatory properties that may help with conditions such as arthritis. People with osteoarthritis, specifically, often also take glucosamine supplements. This natural compound is found in cartilage, the tissue that surrounds joints. With conditions like arthritis, chronic inflammation may lead to tissue damage, worsening pain, and impeding mobility. Glucosamine supplements, which can be harvested from shellfish or lab-created, can reduce the pain associated with these conditions. It may also slow disease progression by protecting the joints.


Ashwagandha is an herb that’s been used in Ayurvedic medicine for more than 3,000 years. An adaptogen and anxiolytic can help reduce stress and anxiety by reducing the production of cortisol, the stress hormone. Some studies suggest it may ease depression symptoms as well. This ancient medicinal may also improve concentration, sleep, energy levels, and insulin sensitivity.




Dietary Supplements and CBD Oil: All You Need to Know from Vitamin A to Zinc